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ea0035oc5.5 | Adrenal & Thyroid | ECE2014

Validation of follicular thyroid cancer molecular classifier in fine-needle aspiration biopsy samples

Pfeifer Aleksandra , Bartosz Wojtas , Malgorzata Oczko-Wojciechowska , Aleksandra Kukulska , Agnieszka Czarniecka , Markus Eszlinger , Thomas Musholt , Tomasz Stokowy , Ewa Stobiecka , Jolanta Krajewska , Dagmara Rusinek , Tomasz Tyszkiewicz , Monika Kowal , Michal Jarzab , Steffen Hauptmann , Dariusz Lange , Ralf Paschke , Barbara Jarzab

Introduction: Follicular adenomas (FTA) and carcinomas (FTC) are thyroid tumours that are indistinguishable in the fine needle aspiration biopsy (FNAB). In our previous research we concentrated on post-operative material and developed the classifier, which discriminates the FTC and FTA, based on formalin-fixed paraffin-embedded (FFPE) material. The classifier was based on expression of five genes and gave the promising sensitivity of 71% and specificity of 72%. The aim of the ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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